Prey is a first-person shooter video game developed by Human Head Studios, under contract for 3D Realms, and published by 2K Games, while the Xbox 360 version was ported by Venom Games. The game was initially released in North America and Europe on July 11, 2006. Prey uses a heavily modified version of id Tech 4 to use portals and variable gravity to create the environments the player explores.

The game's story is focused on Cherokee Domasi "Tommy" Tawodi as he, his girlfriend, and grandfather are abducted aboard an alien spaceship known as The Sphere as it consumes material, both inanimate and living, from Earth in order to sustain itself. Tommy's Cherokee heritage allows him to let his spirit roam freely at times and come back to life after dying, which gives Tommy an edge in his battle against the Sphere.